Detection of Δ9-tetrahydrocannabinol (THC) in hair using GC–MS
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چکیده
منابع مشابه
Default Mode Network in the Effects of Δ9-Tetrahydrocannabinol (THC) on Human Executive Function
Evidence is increasing for involvement of the endocannabinoid system in cognitive functions including attention and executive function, as well as in psychiatric disorders characterized by cognitive deficits, such as schizophrenia. Executive function appears to be associated with both modulation of active networks and inhibition of activity in the default mode network. In the present study, we ...
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Male albino rats, injected intravenously or intracerebroventricularly with delta 1-tetrahydrocannabinol (THC), develop mudriasis. The median effective dose of the intravenous administration group was 5 mg/kg THC, whereas that for the intracerebroventricular route was 150 microgram/kg THC. Sympathectomy significantly decreased the THC-induced mydriasis. The mydriatic effect was not influenced by...
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A new high-throughput liquid chromatography / tandem mass spectrometry (LC-MS/MS) method for the quantification of Δ-tetrahydrocannabinol (THC) in suspect plant material and of its principal metabolite, 11-nor-9carboxy-Δ-tetrahydrocannabinol (THC-COOH), in human urine was developed and validated. The separation was performed on a Zorbax SB-C18 column under isocratic conditions using a mixture o...
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Methamphetamine (METH) is a potent psychostimulant with neurotoxic properties. Heavy use increases the activation of neuronal nitric oxide synthase (nNOS), production of peroxynitrites, microglia stimulation, and induces hyperthermia and anorectic effects. Most METH recreational users also consume cannabis. Preclinical studies have shown that natural (Δ9-tetrahydrocannabinol, Δ9-THC) and synthe...
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The availability of potent synthetic agonists for cannabinoid receptors has facilitated our understanding of cannabinoid actions on synaptic transmission in the central nervous system. Moreover, the ability of these compounds to inhibit neurotransmitter release at many central synapses is thought to underlie most of the behavioral effects of cannabinoid agonists. However, despite the widespread...
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ژورنال
عنوان ژورنال: Egyptian Journal of Forensic Sciences
سال: 2014
ISSN: 2090-536X
DOI: 10.1016/j.ejfs.2013.10.001